Boc-AEEA CAS 108466-89-3

Product Name:Boc-AEEA
CAS NO.:108466-89-3
Other Name：Boc-NH-PEG2-CH2COOH
Appearance:Deep Yellow Oily Substance
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Description

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Products Description

Product name	Boc-NH-PEG2-CH2COOH
CAS NO.	108466-89-3
Purity	＞98%
Alcohol	without alcohol
Packaging Type	PP bag /cardboard bucket
Material	pharmaceutical intermediates
Sheet Size	1kg/10kg/20kg
Prodcut Weight	1.2kg/12kg/23kg
Counts	1kg/bag 10kg/bucket 20kg/bucket
Certifications	ISO9001
Shelf life	24 month
MOQ	100 g

Functions

Boc-AEEA (CAS: 108466-89-3) is a structurally exquisite multifunctional bioconjugation linker that plays a pivotal role in modern medicinal chemistry and materials science. Its molecular architecture integrates a Boc-protected amino group, a hydrophilic dimeric ethylene glycol (PEG₂) segment, and an end carboxyl group, forming a trifunctional platform capable of precise manipulation in complex syntheses. This unique design makes it an ideal bridge for connecting diverse functional modules, widely utilized in the development of innovative therapeutics and the fabrication of advanced materials.
In the field of biopharmaceuticals, the core value of this compound lies in its exceptional molecular bridging capability. As a key intermediate in cutting-edge peptide drugs such as semaglutide, tirzepatide, retaglutide, and long-acting growth hormones, it enables stable linkage between active peptide segments and functional groups (e.g., fatty acid side chains). The PEG segment significantly enhances the molecule's water solubility and biocompatibility, while the Boc protecting group ensures the stability and controllability of amino groups during multi-step synthesis, which is crucial for constructing structurally precise long-acting therapeutic agents.
Beyond traditional drug synthesis, Boc-AEEA demonstrates unique advantages in the field of materials science. The carboxyl group at its end and the Boc-protected amino group serve as effective cross-linking sites, enabling polymer chains to be connected via reactions such as amidation, forming a three-dimensional network structure with enhanced mechanical strength, thermal stability, and controlled degradation properties. This characteristic makes it a crucial building block for preparing high-performance hydrogels, smart adhesives, and functional coatings, providing advanced material solutions for tissue engineering and drug-controlled release systems.
Moreover, the amphiphilic nature of this compound enables its extensive applications in the fine chemical industry. Its PEG segment can serve as a hydrophilic head group for synthesizing novel surfactants and emulsifiers, while it also acts as a valuable intermediate for constructing biosensors, molecular probes, and other fine chemicals. This cross-domain versatility fully demonstrates the critical importance of Boc-NH-PEG₂-CH₂COOH as an advanced chemical tool molecule, providing essential technical support for bridging biopharmaceuticals and material innovation.