Dihydroartemisinin

Items

Standard

Results

Appearance

The product is white crystal or crystalline powder; odorless.

Conforms

Solubility

Soluble in acetone, Slightly soluble in methanol or ethanol; and almost insoluble in water.

Conforms

Melting point

145～150℃, with decomposition

145.3～146.4℃

Identification (HPLC)

The retention time of the main peak of the test solution should be consistent with that of the standard solution.

Conforms

Identification (IR)

The infrared absorption spectrum of the product should be consistent with that of the standard (spectrum set 519).

Conforms

Related substances

Number of impurities 0.25%～0.5%≤1

0

Any other impurity≤0.5%

Not detected

Total impurity≤1.0%

Not detected

Water content

≤0.5%

0.09%

Residue of ignition

≤0.1%

0.04%

Assay

98.0%～102.0%

99.8%

Conclusion :

The product is inspected according to the internal control standard of the enterprise, and the results meet the quality standard.

Classification: Pharmaceutical Raw Materials

CAS No.: 71939-50-9

Purity: 98.0%min

Place of Origin: China (Mainland)

Usage : Treat malaria

Brand Name: TNN

Molecular: C15H24O5

Appearance: White powder

Packing & Delivery

Application

Dihydroartemisinin (also known as dihydroqinghaosu, artenimol or DHA) is a drug used to treat malaria. Dihydroartemisinin is the active metabolite of all artemisinin compounds (artemisinin, artesunate, artemether, etc.) and is also available as a drug in itself. It is a semi-synthetic derivative of artemisinin and is widely used as an intermediate in the preparation of other artemisinin-derived antimalarial drugs. It is sold commercially in combination with piperaquine and has been shown to be equivalent to artemether/lumefantrine.

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