The characteristics of aspirin

Analgesic effect of antipyretic, analgesic and anti-inflammatory drugs such as aspirin: it has good analgesic effect on moderate dull pain such as headache, toothache, neuralgia, joint pain, muscle pain and menstrual pain, but has no effect on severe external injury pain and visceral smooth muscle colic. Its analgesic effect is not acting on opioid receptor, so this kind of drug is not addictive, and its analgesic effect is peripheral, such as salicylic acid, which produces analgesic effect by inhibiting PG synthesis.

Analgesic effect of analgesics: it mainly acts on the central nervous system. Most analgesics belong to opioid alkaloids, such as morphine and codeine. Some of them are similar synthetic products, such as pethidine, methadone, fentanyl, analgesic new, etc. They can selectively relieve or relieve the pain sensation at the analgesic dose, but do not affect the consciousness, touch, hearing, etc. at the same time, the mental tension, irritability and other unpleasant emotions caused by pain can also be relieved, which helps to tolerate pain. This kind of medicine has strong analgesic effect, and is mostly used for severe pain. Most analgesics can cause addiction by continuous use, so they are also called addictive analgesics and should not be used for a long time. Most of the analgesics have inhibitory effect on respiratory center, and they may die of respiratory depression when they are poisoned. Most of these drugs produce analgesic and respiratory inhibitory effects by activating opioid receptors, and morphine is the complete agonist of opioid receptors; Analgesics is a partial agonist of opioid receptor; Naloxone is an opioid receptor antagonist, which can antagonize the analgesic effect and respiratory inhibition of morphine.