D,L-Pen-OH CAS 52-66-4

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Product name	D,L-Pen-OH
CAS NO.	52-66-4
Purity	＞97%
Alcohol	without alcohol
Packaging Type	PP bag /cardboard bucket
Material	pharmaceutical intermediates
Sheet Size	1kg/10kg/20kg
Prodcut Weight	1.2kg/12kg/23kg
Counts	1kg/bag 10kg/bucket 20kg/bucket
Certifications	ISO9001
Shelf life	24 month
MOQ	100 g

D. L-Penicilline (CAS: 52-66-4), as an important chiral molecule, has demonstrated multiple application values in the pharmaceutical field. This racemic compound retains its pharmacological activity for direct treatment and has become an indispensable synthetic block in modern drug development. Its value is fully reflected in both clinical treatment and innovative drug development dimensions.
In terms of direct clinical application, this compound exhibits excellent metal chelation ability and immune regulatory function. The thiol groups in its molecules can form stable soluble complexes with excessive heavy metal ions such as copper, lead, and mercury in the body, which are effectively excreted through the kidneys. This mechanism makes it a key drug for treating Wilson's disease (Wilson's disease). At the same time, it can react with cysteine to generate soluble mixed disulfides, significantly reducing the concentration of cysteine in urine and providing an effective treatment option for patients with cystinuria. In the field of autoimmune diseases, this compound can be used as a slow acting anti rheumatic drug to improve the clinical symptoms of rheumatoid arthritis, and has shown potential value in the treatment of diseases such as scleroderma and chronic active hepatitis.
In the field of drug development, the importance of D, L-penicillamine as a key intermediate is increasingly prominent. It is an important synthetic block for Johnson&Johnson to develop oral IL-23 receptor cyclic peptide inhibitors, and its molecular structure is crucial for constructing cyclic peptides with specific biological activities. More importantly, this compound is the core chiral intermediate for the synthesis of a series of HIV-1 protease inhibitors, which show strong anti AIDS potential by blocking the viral replication cycle. It is worth noting that D-penicillamine and L-penicillamine show significant differences in biological activity: D-penicillamine is mainly used for the treatment of rheumatoid arthritis and shows new therapeutic prospects, while L-penicillamine can be used for spasticity induction and the development of AIDS therapeutic drugs.

The multifunctional properties of this racemic compound make it an important bridge connecting traditional therapy with modern precision drug development, and continue to play an irreplaceable role in the field of medicinal chemistry.

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