L-Pen-OH CAS 1113-41-3

Product Name:L-Pen-OH
CAS NO.:1113-41-3
Other Name：L-Penicillamine
Appearance:White powder
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Description

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Products Description

Product name	L-Pen-OH
CAS NO.	1113-41-3
Purity	＞98%
Alcohol	without alcohol
Packaging Type	PP bag /cardboard bucket
Material	pharmaceutical intermediates
Sheet Size	1kg/10kg/20kg
Prodcut Weight	1.2kg/12kg/23kg
Counts	1kg/bag 10kg/bucket 20kg/bucket
Certifications	ISO9001
Shelf life	24 month
MOQ	100 g

Functions

L-Pen-OH (CAS: 1113-41-3) is a strategic small molecule that combines direct medicinal value with key synthetic functions. Its unique molecular structure, including chiral center, thiol group (- SH), and amino group, makes it play a core role in multiple fields from clinical treatment to innovative drug development.
In direct clinical applications, L-penicillamine exhibits classic and irreplaceable pharmacological activity. As an efficient metal chelating agent, it can form stable water-soluble complexes with excessive heavy metal ions such as copper, lead, and mercury in the body and be excreted through the kidneys. This characteristic makes it a first-line drug for treating Wilson's disease, a hereditary copper accumulation disorder. Meanwhile, it is also an important choice for treating cystinuria, as its thiol group forms a soluble mixed disulfide with cysteine, significantly reducing the risk of urinary stone formation. In addition, as a slow acting anti rheumatic drug, it is used to treat severe active rheumatoid arthritis that is ineffective with conventional therapies by regulating T lymphocyte function, reducing rheumatoid factor levels and other immunosuppressive mechanisms.
In the field of innovative drug development, the value of L-penicillamine as a key pharmaceutical intermediate is increasingly prominent. Its molecules are ideal modules for constructing complex bioactive molecules. A prominent example is that it serves as an important synthetic block for Johnson&Johnson's development of oral IL-23 receptor cyclic peptide inhibitors, and its structure is crucial for the key pharmacophores that make up the cyclic peptide. More importantly, L-penicillamine is the core chiral intermediate for the synthesis of a series of HIV-1 protease inhibitors (such as JE-2147 at the clinical stage). This kind of drugs show strong anti AIDS potential by inhibiting viral replication. In addition, its derivatives also serve as key structural units in the development of anticancer drugs (such as AG-3340) and cardiovascular drugs (such as SD-3321), demonstrating broad market prospects.