Dde-Lys(Fmoc)-OH CAS 156648-40-7

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Dde Lys (Fmoc) - OH (CAS: 156648-40-7) is a precision designed double protected lysine derivative with important tool value in modern chemical biology and peptide drug research. Its molecular structure achieves precise control and selective modification of different functional groups in the same amino acid molecule by introducing two orthogonal protecting groups, Dde and Fmoc, on the side chain and α - amino group of L-lysine, providing a key chemical tool for the construction of complex bioactive molecules.
The core advantage of this compound lies in its excellent orthogonal protective properties. The Dde protecting group can be selectively removed under mild hydrazine treatment conditions while maintaining complete stability of the Fmoc group; Subsequently, the Fmoc group can be independently removed under alkaline conditions. This continuous and non interfering deprotection strategy makes it an ideal building block for synthesizing complex modified peptides, such as branched peptides, cyclic peptides, and labeled peptides, greatly enhancing the flexibility and accuracy of peptide synthesis.
As a powerful research tool, Dde Lys (Fmoc) - OH has demonstrated unique value in multiple cutting-edge biological research fields. Based on the known anti herpesvirus (HSV) activity of lysine, this derivative provides a structural basis for the development and research of novel antiviral peptide compounds, which helps to explore the peptide structure-activity relationship and mechanism of action. At the same time, it is also a precise probe for studying the molecular mechanisms of lysine in human metabolic pathways, immune regulation, and inflammatory responses. By targeting and introducing it into specific peptide sequences, it can deeply analyze the effects of lysine modification on protein function and cell signal transduction, providing molecular level insights for the development of new treatment strategies for related diseases.

 

 

 

    

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