FMOC-LYS(ME)2-OH HCL CAS 252049-10-8

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FMOC-LYS(ME)2-OH HCL (CAS: 252049-10-8) is an advanced lysine derivative with precise functional modifications, playing a key role in chemical biology and peptide drug development. Its molecular structure retains the standard Fmoc protecting group while introducing dimethylation modification on the lysine side chain, making it a core chemical tool for exploring protein post-translational modification mechanisms and developing novel therapeutic drugs.
The core value of this compound lies in its ability to accurately simulate the dimethylated lysine modification in natural proteins. Unlike fully methylated analogues, the dimethyl modified state is more widely present in various cellular signaling and regulatory proteins. By directly introducing this pre modified unit in solid-phase peptide synthesis, researchers can prepare structurally uniform and site-specific methylated peptides, providing an indispensable probe molecule for further studying the molecular mechanism of methylation modification in cellular processes.
At the biomedical application level, this compound exhibits multiple values. Based on these carefully designed peptide probes, scientists can systematically analyze how specific methylation modifications are recognized by the corresponding "reader" domains, thereby regulating gene expression, protein interactions, and signaling pathway activity. This not only deepens the understanding of pathological mechanisms such as cancer and metabolic diseases, but also lays the molecular foundation for the development of new diagnostic methods and therapeutic drugs targeting methylation related pathways. Its excellent stability in the form of hydrochloride ensures reliable performance in complex synthesis processes, making it an important bridge connecting chemical synthesis and biological functional research.

 

 

 

    

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