AEEA.HCl CAS 134979-01-4

Product Name:AEEA.HCl
CAS NO.:134979-01-4
Appearance:White powder
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Description

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Products Description

Product name	AEEA.HCl
CAS NO.	134979-01-4
Purity	＞99%
Alcohol	without alcohol
Packaging Type	PP bag /cardboard bucket
Material	pharmaceutical intermediates
Sheet Size	1kg/10kg/20kg
Prodcut Weight	1.2kg/12kg/23kg
Counts	1kg/bag 10kg/bucket 20kg/bucket
Certifications	ISO9001
Shelf life	24 month
MOQ	100 g

Functions

AEEA·HCl (CAS: 134979-01-4) is a highly versatile chemical building block with extensive applications. Its unique molecular structure-terminated with a primary amine at one end and a primary alcohol at the other, connected via an ethoxy chain-plays a pivotal role in high-tech fields such as pharmaceuticals, materials science, and fine chemicals. The hydrochloride salt form significantly enhances the compound's stability and reaction controllability, making it particularly suitable for large-scale industrial production.
In the pharmaceutical industry, AEEA·HCl serves as a core starting material for achieving the prolonged efficacy of peptide drugs. It is widely used to construct hydrophilic side chains in cutting-edge medications such as semaglutide, tirzepatide, retaglutide, and long-acting growth hormones. By introducing this flexible PEG-like segment into the molecular structure via its amino group, it significantly improves drug solubility and enhances binding affinity with serum albumin, thereby substantially extending the drug's half-life. This key structural unit is essential for enabling once-weekly dosing regimens.
Beyond polypeptide drugs, this compound demonstrates exceptional versatility in synthetic chemistry. Its terminal amino and hydroxyl groups serve as active reactive sites, participating in crucial reactions such as amidation and esterification, making it an ideal linking arm for constructing complex molecules. This property enables its use as a vital reactant or protecting group precursor in organic synthesis, facilitating the production of high-performance polymers, specialty surfactants, and functional dyes.
In addition, the application of AEEA·HCl in materials science and biotechnology is continuously expanding. Its bifunctional group characteristics in the molecular structure make it an ideal cross-linking agent, suitable for constructing hydrogels, adhesives, and smart coatings with specific mechanical strength, thermal stability, or responsive degradation functions. Simultaneously, as a spacer arm in bioconjugation, it effectively connects drug molecules with antibodies, proteins, or targeting ligands, playing an indispensable role in the development of novel antibody-drug conjugates and diagnostic reagents, providing advanced chemical solutions for precision medicine.