Fmoc-AEEA-AEEA CAS 560088-89-3

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Product name	Fmoc-AEEA-AEEA
CAS NO.	560088-89-3
Purity	＞98%
Storage conditions	2-8 ℃
Alcohol	without alcohol
Packaging Type	PP bag /cardboard bucket
Material	pharmaceutical intermediates
Sheet Size	1kg/10kg/20kg
Prodcut Weight	1.2kg/12kg/23kg
Counts	1kg/bag 10kg/bucket 20kg/bucket
Certifications	ISO9001
Shelf life	24 month
MOQ	100 g

Fmoc-AEEA-AEEA (CAS: 560088-89-3) is an advanced structural unit with precise regulatory functions in the development of high-end peptide drugs. Its molecular structure is constructed by repeating AEEA modules to form an extended hydrophilic bridging chain, which is protected at one end by Fmoc groups. This design makes it a key tool for optimizing the physicochemical properties and biological distribution characteristics of therapeutic macromolecules.
The core value of this compound lies in its ability to provide predictable conformational freedom and hydrophilic properties for peptide molecules. As a key intermediate in cutting-edge therapies such as semaglutide, tilpotide, ritaglutide, and long-acting growth hormone, the introduction of regular polyether side chains can effectively enhance the hydration of drug molecules and reduce unnecessary intermolecular interactions through steric hindrance effects, thereby significantly improving drug solubility and inhibiting its aggregation tendency.
At the basic research level, Fmoc-AEEA-AEEA provides an ideal model for exploring the relationship between molecular structure and function. Researchers use this precisely controlled molecular architecture to systematically study the intrinsic relationship between chain length, flexibility, and biological activity, deepening their understanding of chemical reaction mechanisms. These studies directly promote the design of new materials, the establishment of efficient drug screening platforms, and the in-depth exploration of the mechanisms of action of bioactive molecules.
In the field of translational applications, this intermediate has become a strategic tool for pharmaceutical chemists to optimize candidate compounds. By integrating it into molecular design, it is possible to finely regulate the lipophilic balance, conformational flexibility, and surface properties of candidate drugs, thereby affecting their interaction patterns with biological targets, metabolic stability, and overall pharmacokinetic characteristics, ultimately providing a solid chemical foundation for the development of a new generation of biopharmaceuticals with more therapeutic advantages.

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