FMOC-LYS(ME3)-OH HCL CAS 201004-29-7

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Fmoc Lys (Me3) - OH · HCl (CAS: 201004-29-7) is a precision chemical biology tool with unique biological functions. As a high-purity synthesis module for trimethylated lysine, its value far exceeds that of conventional protected amino acids, providing a key means for precise simulation and exploration of protein post-translational modifications in peptide synthesis.
The core feature of this molecule is the complete trimethylation modification of its side chains. This structure accurately simulates the important epigenetic marker trimethylated lysine in histones and other proteins. By directly introducing this block into solid-phase peptide synthesis, researchers can efficiently prepare uniform peptides carrying specific epigenetic signals, completely avoiding the problems of incomplete modification and site-specific control in traditional biochemical methods, and providing a structurally defined chemical probe for epigenetic mechanism research.
At the application level, Fmoc Lys (Me3) - OH · HCl has become a powerful tool for decoding epigenetic codes. Based on these precisely prepared peptide probes, scientists can systematically study how trimethylation modifications are recognized by specific "reader" domains, thereby regulating gene expression, cell differentiation, and disease progression. This not only advances the fundamental understanding of epigenetic mechanisms such as cancer and neurodegenerative diseases, but also provides screening tools and candidate molecules for the development of innovative drugs targeting epigenetic pathways.
In addition, its stable hydrochloride form ensures excellent storage stability and solubility, while the Fmoc protecting group is fully compatible with standard solid-phase synthesis processes. These characteristics make it an ideal bridge connecting synthetic chemistry and biological functional research, effectively promoting the development of the cutting-edge interdisciplinary field of chemical epigenetics.

 

 

 

    

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